Bridgedale Socks are very popular in the UK.
I wear 2 layers of socks and I've always had no problem but it's not a fool proof option. I know people who use 2 layers and still get blisters.
The liner sock I use is a Bridgedale Coolmax Liner http://www.bridgedale.com/men-s-coolmax ... outdoors-1
and the thick sock on top a Bridgedale Trekker http://www.bridgedale.com/men-s-trekker-essential-kit
I've never been one to get major blisters, I have tabbed before on a single pair of socks but I know plenty of guys who use that combo of socks with good results.
Of course if you get persistent problems you should consider taping up your hot spots and reevaluating your footwear. Make sure boots are properly worn in and correct fitting. And as Conker has pointed out, talc your feet. I was always told that my feet should look like the scene from Scarface when Al Pacino face plants his bowl of coke but I've found a fine layer is enough otherwise it can clump.